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//www.pngnrlbid.com [quote="bUsTiNyAbALLs":9q9d2t35]Do not converse with me you filthy minded deviant.[/quote:9q9d2t35] [quote="vastman":9q9d2t35]My rage isn't impotent luv, I'm frothing at the mouth actually.[/quote:9q9d2t35]:



Quote: Richie "So if they're not responsible for the breakthrough, why are the gov giving them a patent on the medicine? Or is something else creating a single supplier monopoly?'"
Conservative fiscal ideology.

Quote: Richie "No it didn't.
Where and how do you differentiate between small, medium and large businesses? Why do you think different sizes of business behave differently? After all, they're still just people running them. If you say we're discussing just big business and not small business and medium business, you really should show how you define the different sizes, and why you think they behave differently at different sizes, if they do behave differently.
BTW, I would be more inclined to trust a big business with shareholders and public perception to worry about, than a sole trader. '"
You can trust who you like. Im neither arguing in favour nor against big business in relation to small businesses, Simply saying they are different and small business is not relevant here.

Quote: Richie "Can you show me a serious post I made where I said I wouldn't trust a doctor and didn't believe the state should have any role in drug development?'"
Considering your response to me saying that government should have the role of developing and prescribing drugs was
Quote: Richie "You can never trust the state. The one business with the most scope to create and abuse a monopoly.'"
that.

Quote: Richie "No, you were condemning millions of doctors and people throughout the world as if they would let you die to earn a few more pence. It's a poor view of people and humanity you have.'"
No I was describing a specific case, an actual and documented thing that happened. Where numerous times, even whilst knowingly being investigated for it, a Big Pharma company offered inducements to Doctors (in America) to prescribe a certain drug even if not the best, for off-label uses, that same company has been found to use misleading and cherry picked statistics. That company was fined $3Billion for its actions. In other cases it paid fines for not disclosing information it held regarding drugs which caused heart attacks. $1billion of this fine was not for any civil claim, but criminal culpability.

This isn’t unique to GSK. AStrazeneca, Eli Lilly, and Johnson and Johnson have all billions of dollars in fines for doing the same thing. It is estimated that $2billion dollars have been paid by Big Pharma to individual Dr’s to prescribe drugs for uses they aren’t valid for and just to the top 20 cases in the US have resulted in fines of $20billion. Yet these companies are still profitable.

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Quote: SmokeyTA "Conservative fiscal ideology. '"


At least argue a point here, if you've gone one.

Quote: SmokeyTA "You can trust who you like. Im neither arguing in favour nor against big business in relation to small businesses, Simply saying they are different and small business is not relevant here. '"

But still not saying where the limits are or why you think one size behaves differently to another.

Quote: SmokeyTA "Considering your response to me saying that government should have the role of developing and prescribing drugs was that. '"

Was it? I've kind of lost track. Was this the thread where you claimed the world economy was zero sum?

Quote: SmokeyTA "No I was describing a specific case, an actual and documented thing that happened. Where numerous times, even whilst knowingly being investigated for it, a Big Pharma company offered inducements to Doctors (in America) to prescribe a certain drug even if not the best, for off-label uses, that same company has been found to use misleading and cherry picked statistics. That company was fined $3Billion for its actions. In other cases it paid fines for not disclosing information it held regarding drugs which caused heart attacks. $1billion of this fine was not for any civil claim, but criminal culpability.

This isn’t unique to GSK. AStrazeneca, Eli Lilly, and Johnson and Johnson have all billions of dollars in fines for doing the same thing. It is estimated that $2billion dollars have been paid by Big Pharma to individual Dr’s to prescribe drugs for uses they aren’t valid for and just to the top 20 cases in the US have resulted in fines of $20billion. Yet these companies are still profitable.'"


Well what evil ers those GPs are. Prescribing the wrong resolution for payment. I wouldn't do it with an IT infrastructure, so to hear doctors are so uncaring is quite a shock.
Should GP practices be considers big or small business?

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//www.pngnrlbid.com [quote="bUsTiNyAbALLs":9q9d2t35]Do not converse with me you filthy minded deviant.[/quote:9q9d2t35] [quote="vastman":9q9d2t35]My rage isn't impotent luv, I'm frothing at the mouth actually.[/quote:9q9d2t35]:



GPS practices in the US are part of some pretty Fsking huge businesses. Thankfully in the UK state control (in the main) has kept us largely from the evil the free market perpetuated in this industry

The Dr's are indeed wrong to do what they did. But if Microsoft for instance were to offer you $500'000 to recommend their product for a use it didn't advertise was part of its capability, but they promised you it was capable of this and provided reams of documentation to back it up would you do it?

Regardless, the Dr's part of the illegal kickback scheme had nothing to do with Merck for example, withholding their data on Vioxx for five years resulting in up to 140'000 cases of serious heart disease nor was it the Dr's who spent $1b fighting the action.

Let's look at that again just to make sure it sinks in. And just add none of this is now disputed. Big Pharma company Merck developed a drug called Rofecoxib (marketed as vioxx) for 5 years they knew that this drug caused serious heart disease. For 5 years they sold Vioxx knowing it caused serious heart problems. The made about $2.5billion per year from selling a drug they knew caused serious heart disease. Merck made, during that time, $12.5billion from selling a drug they knew caused heart disease. During this time up to 140'000 had a heart attack because of it. It is estimated up to 40% of those were fatal.
Merck has spent $1billion fighting wrongful death cases because it's behaviour. It has set aside $5billion for compensation for the up to 60'000 people who died. They had a list of Dr's who had voiced concern about vioxx they set out to discredit. Merck employees sent e-mails about those Dr's saying "We may need to seek them out and destroy them where they live,"www.theaustralian.com.au/news/drug-company-drew-up-doctor-hit-list/story-e6frg6n6-1225693586492

How many more examples would you need to understand that the medicinal market just doesn't work and free market theory is simply not applicable to some industries?

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For those on the pseudo-left who prefer to reinvent history and blame Arthur because they didn't have the bollox to stand up and be counted.

WE TOLD ARTHUR - NO SURRENDER

rlhttps://www.mirror.co.uk/news/uk-news/paul-routledge-miners-can-stand-3006531rl

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A dog is the only thing on earth that loves you more than he loves himself. When you rescue a dog, you gain a heart for life. Handle every situation like a dog. If you can't Eat it or Chew it. Pee on it and Walk Away. "No amount of cajolery, and no attempts at ethical or social seduction, can eradicate from my heart a deep burning hatred for the Tory Party. So far as I am concerned they are lower than vermin. " Anuerin Bevan:d7dc4b20b2c2dd7b76ac6eac29d5604e_19170.jpg



I can't do the fancy talk about the big pharma companies but I can comment on experience. I took part in a clinical trial for my RA at Chappell Allerton Hospital in Leeds for 5 years. I did it for a number of reasons, the main reason was because I had run out of drugs to try at Hull and the other important reason was I thought (and still think) that I gave the pharma company valuable information on how their drug works on me and my disease. Its a slow process, apparently it takes at least 15-20 years for a drug to be developed, tried, tested, approved and prescribed.

I was also on Vioxx from being diagnosed for quite a few years, apparently it was the drug of choice for rheumatology patients, but I was taken off it as soon as it became known in this country about the side effects which I didn't suffer any.

There is no known cure for RA but the therapies that have evolved since I was diagnosed is huge. I have tried 6 different drugs known as biologics and each different one has targeted a different area of the immune system and each one coming a step nearer to halting the disease in its tracks rather than treating the symptoms. I believe a cure will be found in my lifetime.

I see the comments by Americans that their Rheumatologist will only prescribe one drug and one drug only as they get a kickback from the pharma company and I just thank my lucky stars that we don't have the same system over here (or not one that gets so blatently banded about in front of the patient anyway).

What all this has to do with Arthur Scargill I have no idea, but just wanted to put my two penn'oth in icon_smile.gif

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Back on topic - very interesting programme on citizen Arthur on inside/out on BBC north last night.

Seems even his own devotees are turning against him. Forging a letter from a dying man that is pretty low ball behaviour.

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Quote: Sal Paradise "Back on topic - very interesting programme on citizen Arthur on inside/out on BBC north last night.

Seems even his own devotees are turning against him. Forging a letter from a dying man that is pretty low ball behaviour.'"


Some pretty damming accusations against him and his small troika. A massive slush fund from which the top NUM echelon awarded themselves loans, whilst the rank and file batted out a year on strike. His autocratic and secretive decision that he was entitled to a Redundancy package, and without informing, far less obtaining permission from the NUM, writes himself a large cheque in excess of £200k! And what about the hundreds of thousands he's cost the NUM over his antics with that London flat? The very same flat that he tried to buy under Maggie thatcher's Right to Buy legislation, whilst conveniently ignoring the fact it was owned by the NUM!

You have to have a measure of sympathy for the thousands who placed their faith in this guy, and years later find it was their own Union leaders, noses firmly wedged in a Animal Farm stylee in the NUM trough, who royally ed them up the booty.

Maggie must be wetting herself up there......

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She wet herself when she got turfed out of No10.
Did you see the blubbering damsel?
Good old Art set the ball rolling.
Even a sacrificial lamb, as such, of the left.

But we got there.

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Your job is to say to yourself on a job interview does the hiring manager likes me or not. If you aren't a particular manager's cup of tea, you haven't failed -- you've dodged a bullet.:icons077e_files/5454-3678dentheman-msnicons.jpg



Quote: SmokeyTA "GPS practices in the US are part of some pretty Fsking huge businesses. Thankfully in the UK state control (in the main) has kept us largely from the evil the free market perpetuated in this industry

The Dr's are indeed wrong to do what they did. But if Microsoft for instance were to offer you $500'000 to recommend their product for a use it didn't advertise was part of its capability, but they promised you it was capable of this and provided reams of documentation to back it up would you do it?

Regardless, the Dr's part of the illegal kickback scheme had nothing to do with Merck for example, withholding their data on Vioxx for five years resulting in up to 140'000 cases of serious heart disease nor was it the Dr's who spent $1b fighting the action.

Let's look at that again just to make sure it sinks in. And just add none of this is now disputed. Big Pharma company Merck developed a drug called Rofecoxib (marketed as vioxx) for 5 years they knew that this drug caused serious heart disease. For 5 years they sold Vioxx knowing it caused serious heart problems. The made about $2.5billion per year from selling a drug they knew caused serious heart disease. Merck made, during that time, $12.5billion from selling a drug they knew caused heart disease. During this time up to 140'000 had a heart attack because of it. It is estimated up to 40% of those were fatal.
Merck has spent $1billion fighting wrongful death cases because it's behaviour. It has set aside $5billion for compensation for the up to 60'000 people who died. They had a list of Dr's who had voiced concern about vioxx they set out to discredit. Merck employees sent e-mails about those Dr's saying "We may need to seek them out and destroy them where they live,"www.theaustralian.com.au/news/drug-company-drew-up-doctor-hit-list/story-e6frg6n6-1225693586492

How many more examples would you need to understand that the medicinal market just doesn't work and free market theory is simply not applicable to some industries?'"


There are side effects to every drug - I take a number for a heart condition and you can hardly get the pills in the packets for the list of side effects. Viagra was a drug discovered from a side effect

The questions about Vioxx:
1. Did the benefits of the drug outweigh the negatives i.e. did it helps millions - given the size of the sale it must have been widely used. There are plenty of drugs out there with some bad side effects.
2. How many of the 140k had heart attacks as a result of taking the drug and how many would have had them anyway?
3. The question must be asked of the licencing authorities as how a drug with such known side-efects got to market plenty fail at that stage - or did the side effects emerge post general use? Did the drug ever get licenced here?

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Your job is to say to yourself on a job interview does the hiring manager likes me or not. If you aren't a particular manager's cup of tea, you haven't failed -- you've dodged a bullet.:icons077e_files/5454-3678dentheman-msnicons.jpg



Quote: WIZEB "She wet herself when she got turfed out of No10.
Did you see the blubbering damsel?
Good old Art set the ball rolling.
Even a sacrificial lamb, as such, of the left.

But we got there.'"


Only one loser in that battle and it wasn't Maggie!!

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Quote: Sal Paradise "Only one loser in that battle and it wasn't Maggie!!'"


As long as she's resting peacefully now, that's the main. icon_smile.gif

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//www.pngnrlbid.com [quote="bUsTiNyAbALLs":9q9d2t35]Do not converse with me you filthy minded deviant.[/quote:9q9d2t35] [quote="vastman":9q9d2t35]My rage isn't impotent luv, I'm frothing at the mouth actually.[/quote:9q9d2t35]:



Quote: Sal Paradise "There are side effects to every drug - I take a number for a heart condition and you can hardly get the pills in the packets for the list of side effects. Viagra was a drug discovered from a side effect

The questions about Vioxx
Vioxx I think is now licensed again, but now with the side-effects described, and is not often now prescribed. The 140k cases of heart disease were those estimated to be attributed to Vioxx rather than simply general heart disease.

Merck were aware of the issue, they hid their findings and systematically intimidated and attacked those doctors and researchers who tried to bring it to light, that's why it took five years for the truth to be found out.

Drugs do have side effects, however those side effects are part of the prescription decision. What Merck did wrong wasn't that they created a drug which helped some but had a risk of heart attack, but that it hid this risk which meant that it was prescribed to some it shouldn't and offered kickbacks to doctors to prescribe this drug ahead of others whilst hiding this risk but also for symptoms it has never been licensed for

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Your job is to say to yourself on a job interview does the hiring manager likes me or not. If you aren't a particular manager's cup of tea, you haven't failed -- you've dodged a bullet.:icons077e_files/5454-3678dentheman-msnicons.jpg



Quote: SmokeyTA "Vioxx I think is now licensed again, but now with the side-effects described, and is not often now prescribed. The 140k cases of heart disease were those estimated to be attributed to Vioxx rather than simply general heart disease.

Merck were aware of the issue, they hid their findings and systematically intimidated and attacked those doctors and researchers who tried to bring it to light, that's why it took five years for the truth to be found out.

Drugs do have side effects, however those side effects are part of the prescription decision. What Merck did wrong wasn't that they created a drug which helped some but had a risk of heart attack, but that it hid this risk which meant that it was prescribed to some it shouldn't and offered kickbacks to doctors to prescribe this drug ahead of others whilst hiding this risk but also for symptoms it has never been licensed for'"


The FDA must take some blame here - 80 million people were prescribed this drug 99% of which suffered no side effects and probably enjoyed a much improved standard of 'living' i.e. reduced pain. Merck did hide some the side effects but what cannot be contested the drug did a lot more good than it did harm. If you asked the majority of the patients, knowing the potential side effects and the state of their health, I bet most would still have opted for the treatment.

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Quote: WIZEB "As long as she's resting peacefully now, that's the main.
To see Arthur the broken man he is made it all worth while. The man was only interested in one thing - Arthur, the miners were just puppets in his game. Sadly for Arthur he was outplayed, out thought and out manoeuvred by a far cleverer opponent. He was weighed, he was measured and he was found wanting. icon_biggrin.gif

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Quote: Sal Paradise "Sadly for Arthur he was outplayed'"


By someone playing with a stacked deck...

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Castleford
v
Salford
20:00
St.Helens
v
Hull KR
 Sat 8th Mar 2025
     Mens Super League XXX-R3
17:30
Catalans
v
Leeds
 Sun 9th Mar 2025
     Mens Super League XXX-R3
17:30
Warrington
v
Wakefield
17:30
Wigan
v
Huddersfield
 Thu 20th Mar 2025
     Mens Super League XXX-R4
20:00
Salford
v
Huddersfield
 Fri 21st Mar 2025
     Mens Super League XXX-R4
20:00
St.Helens
v
Warrington
20:00
Wakefield
v
Hull FC
 Sat 22nd Mar 2025
     Mens Super League XXX-R4
15:00
Castleford
v
Catalans
17:30
Leeds
v
Wigan
 Sun 23rd Mar 2025
     Mens Super League XXX-R4
15:00
Hull KR
v
Leigh
 Thu 27th Mar 2025
     Mens Super League XXX-R5
20:00
Castleford
v
Hull FC
 Fri 28th Mar 2025
     Mens Super League XXX-R5
20:00
Leigh
v
Wakefield
20:00
Warrington
v
Leeds
 Sat 29th Mar 2025
     Mens Super League XXX-R5
14:30
Wigan
v
Salford
17:30
Catalans
v
St.Helens
 Sun 30th Mar 2025
     Mens Super League XXX-R5
15:00
Huddersfield
v
Hull KR
 Thu 10th Apr 2025
     Mens Super League XXX-R6
20:00
Salford
v
Leeds
 Fri 11th Apr 2025
     Mens Super League XXX-R6
20:00
Hull KR
v
Wigan
20:00
St.Helens
v
Wakefield
 Sat 12th Apr 2025
     Mens Super League XXX-R6
17:30
Warrington
v
Hull FC
20:00
Castleford
v
Leigh
 Sun 13th Apr 2025
     Mens Super League XXX-R6
15:00
Huddersfield
v
Catalans
 Thu 17th Apr 2025
     Mens Super League XXX-R7
20:00
Wakefield
v
Castleford
 Fri 18th Apr 2025
     Mens Super League XXX-R7
20:00
Hull FC
v
Hull KR
20:00
Wigan
v
St.Helens
20:00
Leeds
v
Huddersfield
 Sat 19th Apr 2025
     Mens Super League XXX-R7
20:00
Leigh
v
Warrington
20:00
Catalans
v
Salford
 Thu 24th Apr 2025
     Mens Super League XXX-R8
20:00
Warrington
v
St.Helens
20:00
Leeds
v
Hull KR
 Fri 25th Apr 2025
     Mens Super League XXX-R8
20:00
Salford
v
Leigh
 Sat 26th Apr 2025
     Mens Super League XXX-R8
15:00
Huddersfield
v
Castleford
17:30
Catalans
v
Wakefield
 Sun 27th Apr 2025
     Mens Super League XXX-R8
15:00
Hull FC
v
Wigan
 Sat 3rd May 2025
     Mens Super League XXX-R9
15:00
Leigh
v
Catalans
17:15
Hull KR
v
Salford
19:30
St.Helens
v
Leeds
 Sun 4th May 2025
     Mens Super League XXX-R9
13:00
Huddersfield
v
Hull FC
15:15
Wigan
v
Warrington
17:30
Castleford
v
Wakefield
 Thu 15th May 2025
     Mens Super League XXX-R10
20:00
St.Helens
v
Catalans
 Fri 16th May 2025
     Mens Super League XXX-R10
20:00
Leeds
v
Hull FC
20:00
Wigan
v
Leigh
 Sat 17th May 2025
     Mens Super League XXX-R10
15:00
Hull KR
v
Huddersfield
 Sun 18th May 2025
     Mens Super League XXX-R10
15:00
Wakefield
v
Warrington
17:30
Castleford
v
Salford
 Thu 22nd May 2025
     Mens Super League XXX-R11
20:00
Leigh
v
Hull FC
 Fri 23rd May 2025
     Mens Super League XXX-R11
20:00
Huddersfield
v
St.Helens
20:00
Warrington
v
Hull KR
 Sat 24th May 2025
     Mens Super League XXX-R11
14:30
Castleford
v
Leeds
17:30
Catalans
v
Wigan
 Sun 25th May 2025
     Mens Super League XXX-R11
15:00
Wakefield
v
Salford
 Thu 29th May 2025
     Mens Super League XXX-R12
20:00
Huddersfield
v
Leigh
 Fri 30th May 2025
     Mens Super League XXX-R12
20:00
Hull KR
v
St.Helens
20:00
Salford
v
Wigan
 Sat 31st May 2025
     Mens Super League XXX-R12
14:30
Leeds
v
Wakefield
17:30
Catalans
v
Hull FC
 Sun 1st Jun 2025
     Mens Super League XXX-R12
15:00
Warrington
v
Castleford
ALL SCORES PROVIDED BY RLFANS.COM (SETTINGS)
Matches on TV
Thu 13th Feb
SL
20:00
Wigan-Leigh
Fri 14th Feb
SL
20:00
Hull KR-Castleford
SL
20:00
Catalans-Hull FC
Sat 15th Feb
SL
15:00
Leeds-Wakefield
SL
17:30
St.Helens-Salford
Sun 16th Feb
SL
15:00
Huddersfield-Warrington
Thu 20th Feb
SL
20:00
Wakefield-Hull KR
Fri 21st Feb
SL
20:00
Warrington-Catalans
SL
20:00
Hull FC-Wigan
Sat 22nd Feb
SL
15:00
Salford-Leeds
SL
20:00
Castleford-St.Helens
Sun 23rd Feb
SL
14:30
Leigh-Huddersfield
Thu 6th Mar
SL
20:00
Hull FC-Leigh
Fri 7th Mar
SL
20:00
Castleford-Salford
SL
20:00
St.Helens-Hull KR
Sat 8th Mar
SL
17:30
Catalans-Leeds
Sun 9th Mar
SL
17:30
Warrington-Wakefield
SL
17:30
Wigan-Huddersfield
Thu 20th Mar
SL
20:00
Salford-Huddersfield
Fri 21st Mar
SL
20:00
St.Helens-Warrington
This is an inplay table and live positions can change.
Mens Betfred Super League XXVIII ROUND : 1
 PLDFADIFFPTS
Wigan 29 768 338 430 48
Hull KR 29 731 344 387 44
Warrington 29 769 351 418 42
Leigh 29 580 442 138 33
Salford 28 556 561 -5 32
St.Helens 28 618 411 207 30
 
Catalans 27 475 427 48 30
Leeds 27 530 488 42 28
Huddersfield 27 468 658 -190 20
Castleford 27 425 735 -310 15
Hull FC 27 328 894 -566 6
LondonB 27 317 916 -599 6
This is an inplay table and live positions can change.
Betfred Championship 2024 ROUND : 1
 PLDFADIFFPTS
Wakefield 27 1032 275 757 52
Toulouse 26 765 388 377 37
Bradford 28 723 420 303 36
York 29 695 501 194 32
Widnes 27 561 502 59 29
Featherstone 27 634 525 109 28
 
Sheffield 26 626 526 100 28
Doncaster 26 498 619 -121 25
Halifax 26 509 650 -141 22
Batley 26 422 591 -169 22
Swinton 28 484 676 -192 20
Barrow 25 442 720 -278 19
Whitehaven 25 437 826 -389 18
Dewsbury 27 348 879 -531 4
Hunslet 1 6 10 -4 0
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